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There’s no way to guarantee winning money on Powerball

For all you wise guys thinking of buying every Powerball combo and scooping up a guaranteed $1.3 billion: Think again.

Professional numbers crunchers have done the math and found there’s no way for a New York Powerball player to land in the black by snatching up every possible lottery number, even with this record prize coming up on Wednesday.

There are 292.2 million combinations of the five numbers plus one Powerball number in the game — which means a gambler could spend $584.4 million to guarantee a win by buying every set of numbers.

It may seem like a no-brainer investment, considering the payoff will be at least $1.3 billion. But buying every number would actually be a sucker bet.

Even if playing every number were possible — and experts say it’s not — the winnings could be cut down to just $806 million with a lump-sum payout.

That would be further reduced through taxes. A winner in New York City would take home $502.1 million after taxes, while a state resident outside Gotham would pocket $533.4 million, according to officials.

As bad of a loss as that would be, the real hurt would come if even one other person shared the jackpot by also picking the winning numbers. That would cut the winning prize in half.

Of course, a winner could take the payout over time, which would give them $1.3 billion total. But that would take 29 years of annual payments to collect. It would be much better to just invest the $584 million.

“They’re not stupid,” Scott Norris, a professor of applied mathematics at Southern Methodist University in Texas, said of lottery organizers. “You’re much better off going to a casino.”

The hardest part, though, would be the physical act of buying 292.2 million lottery tickets.

There are no special arrangements for mass ticket buying, so a market-cornering lottery player would need to have a lot of time and pencils to fill out slips at the local bodega.

“No, there is no shortcut to purchasing the tickets,” said Judith Drucker, spokeswoman for the New Jersey State Lottery. “And yes, you would have to fill out [292.2 million] bet slips — which of course would be impossible to do and impossible to process. But certainly it’s an interesting thought.”

No one picked all six numbers for Saturday’s Powerball draw, making this Wednesday’s game the biggest in both US and world history, according to officials.

Lottery fever is spreading fast all over New York. Players think the Willowbrook Deli in Staten Island — where a $101 million Mega Millions ticket was sold last week — is the lucky locale.

“It’s crazy today,” said Navi Singh, 23, brother of the store’s manager. “Customers think that this store might have another chance to get lucky.”

A lottery player in Queens scored a $1 million Powerball prize on Saturday by picking five of six numbers at the Four Season Fresh Farm store in Ridgewood.